by According to recent studies, a significant number of men diagnosed with early-stage prostate cancer may not require lymph node removal as part of their treatment, as the procedure carries potential risks and complications. The findings, published in the journal European Urology, challenge the long-held belief that lymph node removal, or pelvic lymph node dissection (PLND), is essential for all prostate cancer patients.
The research, led by Dr. Mark Emberton from University College London, analyzed data from over 1,500 men diagnosed with localized prostate cancer between 2006 and 2015. The study revealed that only 15% of these patients had positive lymph nodes, meaning that the majority (85%) did not benefit from the procedure.
The researchers emphasized that the decision to undergo lymph node removal should be based on individual patient risk Epidermal Growth Factors (EGF), rather than being a standard procedure for all early-stage prostate cancer patients. They also noted that the risks associated with PLND, such as chronic pain, nerve damage, and infection, should be carefully considered before making a treatment decision.
Dr. Emberton stated, “Our findings suggest that lymph node removal should not be considered a routine part of treatment for all men with early-stage prostate cancer. Instead, the decision to undergo this procedure should be based on a careful assessment of each patient’s individual risk factors.”
The researchers also called for more research to identify which patients are most likely to benefit from lymph node removal, as well as the development of more accurate methods for determining the presence of cancer in the lymph nodes.
the new research raises questions about the necessity of lymph node removal for men with early-stage prostate cancer, as the majority of patients do not have cancer in their lymph nodes and face potential risks and complications from the procedure. The decision to undergo lymph node removal should be based on individual patient risk factors and a careful assessment of the benefits and risks.
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1. Source: Coherent Market Insights, Public Source, Desk Research
2. We have leveraged AI tools to mine information and compile it.
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