Causes of Restless Legs Syndrome Treatment
While the exact causes of RLS are unknown, researchers believe it may be linked to problems with dopamine signaling in the brain. Dopamine is a neurotransmitter that helps control movement and sleep-wake patterns. Low dopamine levels in certain areas of the brain have been associated with RLS. of Restless Legs Syndrome Treatment is also considered a neurological disorder. Some potential contributing factors include:
– Family history and genetics: RLS often runs in families, so genetics may play a role. Close family members are more likely to develop RLS.
– Iron deficiency: Low levels of iron in the blood, known as iron deficiency, is linked to a higher risk of RLS. Iron is important for dopamine production.
– Pregnancy: Up to 40% of pregnant women experience RLS, usually in their third trimester. Hormonal changes are thought to contribute. Symptoms often subside after delivery.
– Kidney disease: Those with chronic kidney disease or end-stage renal disease have a greater chance of RLS. Uremia, or high levels of urea in the blood, may be involved.
– Nerve damage: Sometimes RLS is caused by nerve damage in the legs from conditions like diabetes, alcoholism, or peripheral neuropathy.
Lifestyle and Restless Legs Syndrome Treatment
For mild to moderate RLS, lifestyle changes and over-the-counter treatments are usually recommended first before trying prescription medications. Possible approaches include:
– Getting enough sleep: Aim for 7-8 hours of quality sleep per night. Fatigue makes RLS symptoms worse. Establish a relaxing bedtime routine.
– Reducing stress: Stress has been linked to RLS flare-ups. Try relaxation techniques like yoga, deep breathing, and meditation.
– Exercising regularly: Exercise can help use up restless energy and improve sleep. But avoid intense exercise close to bedtime.
– Limiting caffeine and alcohol: Caffeine is a stimulant and alcohol can disrupt sleep. Cut back or eliminate to see if it helps symptoms.
– Improving iron levels: For those with iron deficiency, take an iron supplement. Make sure to take it along with vitamin C or on an empty stomach for better absorption.
– Hot/cold therapy: Applying heating pads or ice packs to legs during a flare-up may provide temporary relief for some.
– OTC medications: Over-the-counter pain relievers containing acetaminophen, ibuprofen or naproxen are sometimes useful for mild, intermittent RLS.
Prescription Medication Options
When lifestyle changes aren’t enough, prescription medications may be necessary, especially for moderate to severe, chronic RLS. Common drug therapies include:
– Dopamine agonists: Drugs like pramipexole (Mirapex) and ropinirole (Requip) that mimic dopamine’s effects are first-line treatments. They significantly reduce symptoms for many people. However, they carry risks like daytime drowsiness, nausea, and compulsive behaviors.
– Gabapentin/pregabalin: Anticonvulsants in the gabapentinoid class, such as gabapentin (Neurontin) and pregabalin (Lyrica), are also frequently prescribed. They help control sensory and motor symptoms. Side effects can be similar to dopamine agonists.
– Opioids: For severe RLS that does not respond well to other options, opioids like oxycodone may provide relief. But they have greater risks of abuse and dependence compared to other classes. Short-term use only is usually recommended.
– Benzodiazepines: Drugs like clonazepam (Klonopin) may be tried occasionally for short-term relief if symptoms are very disruptive. Dependence is a problem with chronic use.
– Iron infusions: For those with severe iron deficiency, intravenous iron infusions under medical guidance may better treat the underlying cause compared to oral supplementation alone.
Alternative and Complementary Therapies
In addition to standard medical treatments, some find complementary approaches like the following to be moderately helpful:
– Massage therapy: Gentle leg massage before bed may temporarily relieve symptoms for some. It works best when done as part of a sleep hygiene routine.
– Acupuncture: This ancient Chinese practice has shown mixed but generally positive results in clinical trials for RLS. Many experience reduced discomfort.
– Magnesium supplements: Magnesium deficiency has been tied to RLS flare-ups in some studies. Oral magnesium glycinate or magnesium malate may ease symptoms.
– Meditation/hypnosis apps: Practices like mindfulness meditation, guided imagery, and self-hypnosis apps aim to distract from sensations and promote relaxation. Outcomes are variable depending on individual response.
In Summary, while many cases of RLS are mild, it’s important to consult a doctor if symptoms impact quality of life significantly or don’t improve with basic self-care measures. A healthcare provider can properly diagnose and rule out other issues, then prescribe an appropriate treatment plan. Seek prompt medical evaluation for RLS accompanied by any concerning neurological changes or other new symptoms. With proper management, most people living with RLS can gain long stretches of restful sleep.
(LinkedIn: https://www.linkedin.com/in/vaagisha-singh-8080b91)
*Note:
1.Source: Coherent Market Insights, Public sources, Desk research
2.We have leveraged AI tools to mine information and compile it
Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc.