June 13, 2024

Active Pharmaceutical Ingredients Market is Expected to Register High Growth Due to Increasing Demand for Generic Drugs and Biologics

The active pharmaceutical ingredients (API) market is a crucial part of the pharmaceutical industry. APIs are the biologically active components of drugs that provide therapeutic effects. APIs are used in producing medicines for treating various therapeutic conditions such as cardiovascular diseases, diabetes, cancer, central nervous system disorders, and infectious diseases. The increasing prevalence of chronic diseases worldwide has accelerated the demand for affordable generic medicines and biologics. The growing generics market provides significant opportunities for API manufacturers to cater to a wide range of therapies.

The Global Active Pharmaceutical Ingredients Market is estimated to be valued at US$ 249.3 Bn in 2024 and is expected to exhibit a CAGR of 6.1% over the forecast period 2024 to 2031.

Key Takeaways

Key players operating in the active pharmaceutical ingredients market include Teva Pharmaceutical Industries Ltd., Pfizer, Inc., Dr. Reddy’s Laboratories Ltd., Novartis AG, Mylan N.V., Amneal Pharmaceuticals LLC, Lonza Group, Lupin Limited, Fresenius Kabi, Hikma Pharmaceuticals, Cipla Limited, Glenmark Pharmaceuticals Limited, Sun Pharmaceutical Industries Ltd., Endo International plc, Aurobindo Pharma Limited, Apotex Inc, Taro Pharmaceutical Industries Ltd, Stada Arzneimittel AG, Krka Pharmaceuticals, CordenPharma International, Evonik Industries AG, and Biological E. Limited.

Key opportunities in the API market include increasing outsourcing of API manufacturing by pharmaceutical companies and growing demand for generic drugs and biologics across emerging markets. Emerging technologies such as continuous manufacturing technologies, 3D printing, and nanotechnology have the potential to enhance efficiency and flexibility in API production.

Market drivers: The increasing demand for generic drugs and biologics is a key driver accelerating growth of the API market. As drug patents expire, the generics market is expected to capture a larger share of the pharmaceutical industry, benefiting API manufacturers. Additionally, the increasing incidence of chronic diseases worldwide is placing immense pressure on healthcare systems, driving demand for lower cost generic alternatives to patented drugs. This will favor API producers and boost market revenues over the forecast period.

Current Challenges in Active Pharmaceutical Ingredients Market
The active pharmaceutical ingredients (API) market is facing challenges related to complexity in manufacturing processes and stringent regulatory requirements. Meeting international quality standards and ensuring adherence to good manufacturing practices adds to production costs. Further, supply chain disruptions during the COVID-19 pandemic impacted the availability of raw materials. Sourcing APIs from multiple regions is a mitigation strategy but increases logistical challenges. Cost pressures from generics competition also affect profit margins. Innovation in delivery systems can help manufacturers better differentiate products and command premium prices. Overall, balancing quality, regulatory compliance with cost efficiencies will be a key priority.

SWOT Analysis
Strength: Established manufacturing infrastructure and capabilities for producing complex APIs. Wide geographical presence helps serve global market.
Weakness: High dependence on China and India for raw material supplies exposes to supply chain disruptions. Cost control remains a challenge due to evolving quality norms.
Opportunity: Growth in biologics and novel drug delivery mechanisms require innovative API manufacturing technologies. Outsourcing trends allow contract manufacturers to expand service offerings.
Threats: Intensifying price competition from generic drug makers. Stringent regulatory actions for non-compliance could disrupt operations.

Geographical Regions with Highest Market Value
North America and Europe account for the largest share of the global active pharmaceutical ingredients market, in terms of value. This can be attributed to the presence of major pharmaceutical companies with advanced API manufacturing facilities. The United States represents the largest market owing to the high demand for generics and biologics drugs.

Fastest Growing Geographical Region
The Asia Pacific region is poised to grow at the fastest pace during the forecast period. This can be attributed to increasing domestic consumption with growing healthcare expenditures in populous nations such as China and India. Moreover, the availability of cheap raw materials and low-cost skilled workforce have attracted API manufacturers to set up production units. Countries like China, India and South Korea are emerging as manufacturing hubs and export APIs to developed markets.


  1. Source: Coherent Market Insights, Public sources, Desk research
  2. We have leveraged AI tools to mine information and compile it